PhD student position in Medical Science – Clinical Pharmacology at University of Uppsala

Inside solid tumors the individual cells often grow in close vicinity to each other and areas with mild to severe oxygen deficit, hypoxia, is formed within the tumor. The hypoxic tumor cells are likely to be less sensitive against traditional treatment options, e.g. several studies have demonstrated hypoxia-related resistance against radiotherapy. Most probably this is also true for several chemotherapeutic treatments.

Aim: To investigate the activity of different anticancer drugs on:

1. tumor cells cultivated in spheroids, i.e. small micro-tumors (0.1-1 mm) with a hypoxic core
2. tumor cells cultivated under hypoxic conditions in comparison to normoxic conditions,

with special attention to drugs with potentially increased hypoxic activity and their mechanisms.

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Position as PhD student in developmental psychology. The project that is the financial basis for the position concerns the relation between aggression and cognitive control functions (so called executive functions) in children, and how these factors longitudinally are related to peer relations.

Qualifications: The applicant must have a basic university degree with psychology as a major subject.

Specific Qualifications: Experience of performing testing and working with children, as well as shown administrative independence are considered as additional qualifications. Good knowledge in Swedish and English is required.

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Uppsala University hereby declares the following position to be open for application: PhD student position in Astronomy or Space and Plasma Physics at the Department of Physics and Astronomy

Are you interested in studying dynamical processes in young and evolved stars, the early evolution of galaxies, the origin of the chemical elements, the enrichment of interstellar matter with gas and dust from evolved stars, the formation of the solar system and other planetary systems, asteroids and comets, how the solar wind can penetrate the Earths protective magnetic field and how it affects other bodies in the solar system, energy transport and particle acceleration in space, and other space plasma phenomena?

Are you interested in using satellite clusters, analysing data from Saturn and its moons Titan and Enceladus, studying space with large radars, observing with the worlds largest telescope VLT in Chile, analysing data from space telescopes, or modelling phenomena and objects in space with supercomputers?

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A PhD scholarship in Life Sciences has been announced for the academic year 2011. The PhD scholarship is in association with the Institute of Nuclear Sciences, France. The research area for this PhD scholarship is Biochemistry/ Life sciences.

The PhD scholarship thesis aims at developing, in partnership with a clinical-research team, a series of original diagnostic tests and a therapeutic monitoring of type 1 diabetes. In comparison with existing technology, the goal of this work is to develop rapid tests (less than 5 hours), quantitative and easy-to-use in clinical routine.

If an early and efficient diagnostic test for diabetes is important, it is even more critical to get a reliable test allowing to evaluate the beta cell mass. That’s the reason why, in parallel, and in order to improve the management and the quality of life for diabetic patients, we will try to develop a preclinical imaging agent for the beta cells utilizing antibodies produced in our laboratory.

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